I joined just to comment on this thread :)   I'm 6'6" 280.  I wear a 2XLT and 40ish/36 pants.  42 is usually too big but 40 can be snug.  40 would be perfect if I lost another 10 lbs, lol.  Anyway, the inseam is always the problem, not the waist.  36" inseam is rare, and usually only in either 38 or under or 44 and over.  I don't understand that.  Trying to find "performance" pants (fry fit, stretch, etc) is an exercise in futility.  Also, it's nearly impossible to find...