I'm 47 and have been lifting on and off since 14. I have never looked like anyone that stars in an action film. A few years back my wife was treated for 2-3 different types of cancer. Between surgeries, radiation tablets and hormone treatments she was left rather "wilted". Last year I bought her a golf pass and she started getting some mileage in walking the courses we play. Unfortunately, although she was getting her legs back in shape, she was struggling trying to hit 75 yard drives.
So, we signed up at a local rehab center which has a well stocked Nautilus circuit and we started do Super Slow/Power of 10/Body by Science workouts. She is starting to gain muscle mass in her shoulders and hips, and I am losing weight lifting the prescribed 1-2 days a week and cutting my food intake to three one plate meals a day. (No S Diet)
I do use a Bullworker as well. But, too much gives me shoulder issues.
Best of luck with your wife's treatments. May you have many many rounds together as she gets stronger and you get buff.