Oh yes it will. At least on where he will be drafted.
Before the BCS game, he was considered a mid-first round pick, somewhere in the teens. His horrible showing there will easily drop him out of the first round. Now this concocted dead girlfriend story will have a lot of teams passing on him. Goes to character, let's face it, intelligence. Two traits highly valued by NFL teams.
I can see him dropping to the third round where some team will consider him a 'value' pick. So that stunt cost him millions of contract dollars.
Now, once drafted, will this have an effect on his career? On this I agree with billchao. There's nothing to indicate this story will impact how he plays at that level - what is more alarming was how he disappeared in the BCS title game.
Really? On the boards I've seen, they had him going first overall to KC. Now, I saw an updated one (Jan.4th) where he was going 5th overall to Detroit, but this was before the National Championship, where he obviously had a bad game.