I put Erik's recommendation into practice in my last league round. The last par 5 (565 yd and 1 hdcp), my drive went right. My second shot left me with a 180 yd uphill shot from the left rough on a side hill lie with the ball above my feet. Instead of laying up to 100 (there is a hazard from 95 - 80 in), I used my 3H (normal 190 yd club) and aimed for the fairway just short of the green. Long is bad because it is a multi-tier green with steep slopes and ridges. Left and right are deep traps.
My shot ended up about 5 yards short of the green. I chipped up but past the hole by 6 feet and missed the dang putt. But the strategy definitely put me into position to par a very tough hole for me.