Reading the rule, I think Fourputt is right, as ridiculous as it might be.
Imagine this scenario. Standing the tee of an easy par 5 that I get no strokes on. My ESC is 7. I hit my tee shot and lose it, unexpectedly. I have the following options: (1) retee and hope to shoot a 6; (2) pick up and post a 7 under Rule 4-1; or (3) take a drop where it went out, without a penalty--and no matter what I shoot thereafter, even if its an 8--record a 5 under Rule 4-2.
The same options would be present if you hit it OB. Or anytime you commit a penalty, you could just not penalize yourself and take a par or bogey.