I play in a weekley simulator league.
There are things that translate well and those that don't. Distance, spin, flight path are all pretty accurate. but, you have to remember that the simulator lines you up perfectly every time. Not only is the screen airmed directly at you target, but you also have walls, and even lines on the ground that help you aim straight. So, if you have alignment issues, you'll hit more fairways and greens in a simulator than in real life.
Additionally, Simulators are really great for dialing up your wedge distances, but remember that doesn't really account for turf interaction. so, take those distances with a grain of salt. A well struck, crisp pitch shot in a simulator will be equal to a well struck, crisp pitch shot outside. but mishits, especially fat ones, are forgiven much more in a simulator.
Lol well of course there are countless factors to be accounted for but i would hope that things like accuracy off the tee, distance control (knowing them in ideal conditions and adjusting for shot conditions later on the actual course), and course management would be some things you could take away.