Personally, I have a special place in my heart because Titleist has always made, in my mind, players clubs. Thinner top lines, increased workability, and solid feel. As iacas said, Titleist makes a club for better players. And to be honest, that is part of the appeal of the brand.... there is some exclusivity associated with it.
Branding is a big part - Vokey wedges....Scotty Cameron putters - Titleist has done a fantastic job branding their clubs, and making sure that those key pieces of equipment, wedges and putters, have been consistent over the years.
As far as wedges go - Titleist makes great wedges....and they are consistently great. Rarely do you see a 'form forged' screw up like Cleveland had. Granted, Cleveland makes fantastic wedges too.
Mizuno has a similar story. Their irons are PURE, and they have historically been geared towards better players. Granted, they've started to put out a lot more clubs in the past few years to try and broaden their customer base. At heart, they are still a club that good players love.
In my opinion, its somewhat cyclical. Both brands are associated with better players, and in turn, better players gravitate towards those clubs (an interesting phenomenon). I'll readily admit that when choosing clubs, the stigma around them does affect me a little bit. Hogan, Titleist, and Mizuno have special places in my heart because they make, on the whole, clubs geared towards the better player.