When I'm playing to bring in the lowest score, I like to work on playing the strengths in my game. Right now, my strengths would be my irons and wedges, the putting and 4w are mediocre, and the driver is my main fault. I've recently been able to leave my driver in the bag in places where I know it is not necessary, setting my pride aside, and I was able to achieve my best score of 79 on a par 72. The only time I bring out the driver is on holes where the fairway is open to the right and accuracy is not a huge deal, then I try and take advantage of the extra yardage. Otherwise I will accept a playable drive of ~235 in the fairway from the 4w.
Also, having some recovery shots in the bag is a crucial thing. My favorite is the punch-draw for when you end up in the trees. It is an easy shot to execute and very controllable.