Having wasted years at the range hitting buckets...I have two routines:
The first is similar to what others have mentioned...I pretend it is a hole. I drive, hit a second shot, and usually pitch/lob/etc. Sometimes it is a par 5, and I break out the 3-wood/hybrid, other times it is a short/long par 4 where I utilize my middle irons. Just depends. However, I always try to pace myself...hit a ball...step away...watch the guy next to me hit a ball, then I might hit my shot. Pace is important for my game. I like to think of it as simulation-time.
The second is when I am trying to correct or add something to my game. Because I have been playing courses more recently, I have really concentrated on my shots inside 100 yards at the range. That means spending a lot of time hitting different shots with my pitch, sand, and lob wedge.
I always find a target too. I don't care if it is brown section of grass or a tree in the distance.